Non-FDA Approved Treatments

Non-FDA Approved Hair Loss Treatments for Regrowth

When it comes to dealing with hair loss, many look beyond FDA approved treatments, like finasteride and minoxidil. Non-FDA approved hair loss treatments cover a range of options, from experimental compounds to off-label drug use. These options can be attractive to those seeking alternatives that can offer faster or better results. They can also offer treatment for conditions not fully addressed with conventional medications. While many of these treatments show potential through research and clinical studies, they lack the testing to ensure safety and efficacy.

Close up showing before and after results dermarolling (microneedling) and minoxidil to treat hair loss Non-FDA Approved

Min & Dermarolling

A combination of a topical hair growth stimulant and microneedling to enhance synergistic effects to promote hair growth.

Before and after using setipiprant and pge2 to regrow hair on balding temples Non-FDA Approved

Setipiprant & PGE2

A duo targeting hair loss by blocking prostaglandin D2 and promoting hair growth with prostaglandin E2.

RU-58841

A topical anti-androgen that binds to androgen receptors in the scalp to prevent DHT-related hair follicle miniaturization.

CB-03-01

A topical anti-androgen that reduces androgen activity in the scalp without systemic hormonal effects.

Pyrilutamide

A topical androgen receptor antagonist designed to inhibit DHT effects on hair follicles to promote regrowth.

Spironolactone

An oral or topical medication that blocks androgen receptors and reduces DHT levels to stop hair loss.

Latanoprost

A prostaglandin analog originally for glaucoma, repurposed to stimulate hair follicle growth and density.

Ketoconazole

An anti-fungal shampoo with anti-inflammatory and mild anti-androgenic properties to reduce hair loss.

Fluridil

A topical anti-androgen that deactivates DHT in scalp tissues to protect hair follicles and promote regrowth.

Procyanidin B2

A natural compound from apples shown to promote hair growth through antioxidant and growth-stimulatory effects.

Stemoxydine

A topical treatment that promotes hair regrowth by mimicking hypoxic conditions to awaken dormant follicles.

How to Mix

A comprehensive guide to safely and effectively mixing your own custom hair loss treatment solutions tailored to your needs.

Understanding Non-FDA Approved Hair Loss Treatments

Non-FDA approved hair loss treatments cover a variety of options that are not officially endorsed for hair loss. These treatments can range from experimental compounds to off-label use of medications. While some have shown promise in studies, their efficacy and long-term effects are less known compared to FDA approved options.

Experimental topical treatments like RU-58841 and CB-03-01 are gaining popularity for their anti-androgenic properties, applied topically. These target dihydrotestosterone (DHT) to prevent hair follicle miniaturization. Similarly, pyrilutamide is another topical anti-androgen being explored for its potential in reducing male pattern baldness progression. Due to their limited large-scale studies, these options remain outside of mainstream medical recommendations. Other compounds, like procyanidin B2 and fluridil are also used for their antioxidant and hair-strengthening effects. While these treatments appear to be safe based on research, they still lack the long-term testing needed for regulatory approval. Some options repurpose existing medications for hair growth. Latanoprost was originally used for glaucoma but has shown potential in stimulating eyelash and hair growth. Ketoconazole is an anti-fungal that offers anti-inflammatory and mild anti-androgen benefits to help reduce hair loss.

Combining non-FDA approved treatments or creating custom solutions has become increasingly popular among those suffering from hair loss. While these treatments have been used successfully to regrow hair, the lack of FDA approval means a higher individual risk.